Volunteer human could solve some of the issue only, afterall there are thousands of drugs being research and develop by different pharmaceutical companies, and getting enough patients of the right conditions are difficult.
And when it comes to human life, its usually get much more complicated when a new experimental drug went wrong. (if not test prior on animals, the toxicity might only be revealed when human test subject were used and that might lead to death)
recent example: https://www.statnews.com/2017/06/08/french-fatal-clinical-trial-off-target/
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