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RE: What The Human Genome Project Discovered About Who We Are

in #biology7 years ago

@alexander.alexis nice post but you may want to edit this line "The rest of the genome is biologically non-functional, usually called non-coding DNA. " This line a misleading, as we know that a lot of the non-coding DNA does in fact have biological function such as ribosomal RNA genes, micro RNAs, tRNAs, lncRNAs, telomere and centromere sequences etc. The Encyclopedia of DNA Elements (ENCODE) project showed that about 80% of our genome has biological activity.

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Yeah I was debating this in my head, and there seems to be some external debate as well! I'll link to this and let people do some of their own research.

I think that the transponsons are equivalent to the inelegant excess codes in modern computer programs.

Back when the cutting edge of programming was compiled on IBM 386 computers, programming code needed to be streamlined and efficient. In our decandent modern day of excess computing power, such careful code editing is unnecessary. Now, codes are pasted on top of each other without regard because the excess computing power overcomes programming obtuseness.

Similarly, when ATP began growing on mitochondrial trees, the biological programming code no longer needed to be elegant. The cells could afford to paste DNA on top of each other without dying of ATP exhaustion in replication or synthesis.

It's true that, by and large, the smaller the organism, the less transposons there are, and at tiny scales the organism must be extremely efficient and can't afford 'junk'.

Thanks for sharing the link. I went to the original paper and did not realize there was so much debate on how molecular biologist and evolutionary biologist define "function".
Cheers!