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Yes and no. It depends on the project. I had invested in TRX when it was 3 cents and saw it 5x itself in a few weeks. Best I can recommend is yes the amount of supply does matter a bit, but what really counts is if you believe in the project. Of course were all looking for some sort of gain, but in the long run I'm sure when you do your due diligent research and find one you really like you'll see gains on it. Now remember to always hold and never sell at a lost. Wish you the best!