The one we have really made big gains on is Smartcash - thankfully we were able to make a bunch on Bitcoin and them dump it and buy lots of altcoins that have gone up too.
We are mid term - 3-12 months investors on most of them, but if Smartcash becomes the new Bitcoin we are made :)
I tend to choose the coins but Deb handles the exchange stuff - that just spins me out, so geek...