I absolutely deplore youtube and avoid it wherever possible, but I always have trouble with D tube. It lets me upload vids and then they won't play because they are not in an acceptable format. I've tried using various incarnations of mp4, mpeg, & avi and it won't play any of them.
I understand it's not being developed by a team with endless resources, so they can't compete with the likes of google but it does seem very selective on what it will accept in regards to video formats.
If it had been written in HTML 5 from the outset so it would been compatible with no script too. I have to drop most of my security to run javascript platforms.
All that said I love the concept of D Tube and I really hope it takes off.