Sambiloto (Andrographis paniculata Ness) is a wild plant that grows in many gardens, riverside, in the yard, moist open land and other open places. This terna plant (shrub) is easily found in the lowlands to the plains with an altitude of 1600 mdpl (meters above sea level).
Wild plants that have long been known to have medicinal properties is said to originate from the Tropical Asia region. Sambiloto is an annual herbal plant that is included in the family Acanthaceae. Sambiloto leaves have benefits and benefits to treat various types of diseases, both minor and serious illnesses. From the results of various studies to prove that sambiloto leaves contain various chemical compounds that are efficacious as a medicine. Given the content and function of these plants, currently sambiloto much studied to be developed as raw materials for modern medicine, such as the use of sambiloto as an HIV drug and anti-cancer.
Sambiloto plants are widely found in Indonesia, Malaysia, Thailand and some regions in the Americas.
Sambiloto plant has become a plant that is widely known to have efficacy as an herbal medicine.
For people who live in urban areas or can only visit the village occasionally, it is less likely to recognize the name of the bitter plants.
Sambiloto plant is known by various local names or regional names, namely Ki oray, ki peurat, takilo (Sunda). bidara, sadilata, berdata, takila (Java). pepaitan (Sumatra); Chuan xin lian, yi jian xi, lan he lian (China), xuyen tam lien ,; cong cong (Vietnam). kirata, mahatitka (India / Pakistan); Creat, green chiretta, halviva, kariyat (English).
The main component of sambiloto is andrographolide which is useful as a medicine ingredient. In addition, the bitter leaf contains saponins, falvonoid, alkaloids and tannins. Other chemical substances contained in the leaves and stems are laktone, paniculin, kalmegin and yellow crystal that has a bitter taste. All parts of bitter plants, such as leaves, stems, flowers and roots, are very bitter if eaten or boiled for drinking. The bitter taste is caused by the presence of andrographolid compounds that are found in the plants sambiloto, especially the leaves and stems.
The leaves and branches contain lactones consisting of deoxygrapholids, andrographolid (bitter substances), neoandrografolid, 14-deoxy-11-12-didehydroandrografolid, and homoandrografolid. There are also flavonoids, alkane, ketones, aldehydes, minerals (potassium, calcium, sodium), acrid acid, and resin. Flavotioids are most widely isolated from roots, ie polymetoxiflavones, andrographin, pan.ikulin, mono-0-methylwithin, and apigenin-7,4-dimethylters. Andrografolid active substances proved efficacious as hepatoprotektbr (protect liver cells from toxic substances).
Benefits of Leaves Sambiloto
Sambiloto leaves are known to be efficacious for treating various types of diseases, among others, to cure hepatitis, bile duct infection, bacillary dysentery, typhoid, diarrhea, Influenza, tonsillitis (tonsillitis), lung abscess, malaria, Pneumonia, inflammation of the airways (bronchitis), acute kidney inflammation (pyelonephritis), middle ear inflammation (OMA), appendicitis, toothache, fever, gonorrhea, diabetes mellitus, tuberculosis lung, skrofuloderma, whooping cough (pertussis), shortness of breath (asthma), leptospirosis, high blood (hypertension), leprosy (morpus hansen = leprosy), mushroom poisoning, cassava, tempe bongkrek, seafood, trophoblast disease, hydatidiform), malignant trophoblast (trophoblast tumor), and lung tumor.
How To Process Sambiloto Leaves For Treatment
Dry herbs (whole parts of plants ie roots, stems and leaves) 10 - 20 g of boiled or dried herb finely ground into a powder then brewed, drunk or 3-4 times a day. For the treatment of cancer, intravenous fluids, injections, or tablets are used. For external use, fresh ingredients are boiled and water is used for washing or finely ground and placed in a sore place, such as poisonous snake bites, itching, or ulcers.
How to Process and How to Make Leaf Drug Sambiloto
*** Typhoid Disease (Typhus, Typhoid Fever)**
Sambiloto leaves fresh as much as 10 - 15 sheets boiled with 2 water glass until remaining 1 glass. After the cold is filtered, add it honey to taste and then drink at once. Do it 3 times a day.
*** Basiler dysentery disease, Diarrhea, inflammation of the airways, pneumonia**
Dry herbs as much as 9-15 gr boiled with 3 cups water to the remaining 1 cup. After cold filtered. Drinking water 2 times a day, each 1/2 cup.
*** Disease Dysentery**
Fresh purslane herb (Portulaca oleracea) of 500 g was evaporated for 3 - 4 minutes, then crushed and pressed. The accumulation of juice is added with 10 g of bitter powder while stirring. The mixture is then drunk, a day 3 times each 1/3 part.
*** Influenza Disease, Headache, Fever**
Sambiloto dry powder as much as 1 g brewed with a cup of hot water. After the cold just drunk at once, Do it 3-4 times a day.
*** Fever Disease**
Sambiloto leaves as much as 1 handful of crushed. Add it 1/2 cup clean water, strain and drink at once. Fresh finely ground leaves can also be used as a hot body poultice.
*** Pulmonary TB disease**
Sambiloto dried leaves are ground into powder. Add honey to taste while stirring evenly then made pills with a diameter of 0.5 cm. This pill is drunk with water. A day 2 - 3 times, each times taking 15 - 30 pills.
*** Whooping cough (pertussis), High blood**
Sambiloto leaves fresh as much as 5 - 7 pieces brewed with 1/2 cup of hot water. Add honey to taste while stirring. After a cold drink at once. Do it 3 times a day.
*** Pneumonia, Inflammation of the mouth, Tonsillitis**
Dried herb dried herbs as much as 3- 4.5 g brewed with hot water. After the cold add honey to taste and drink at once.
*** Pharyngitis pharyngitis**
Sambiloto fresh herbs as much as 9 g washed and then rinsed with water
warm. The material is then chewed and swallowed.
*** Slimy nose (rinorea), Middle ear infection (OMA), Toothache**
Sambiloto fresh herbs as much as 9-15 g boiled with 3 cups of water until the remaining 1 cup. After cold filtered, then drink 2 times a day 1/2 cup. For OMA, fresh herbs are washed and finely ground and squeezed. The water used for ear drops.
*** Diabetes**
Sambiloto leaves fresh as much as 1/2 handheld washed and boiled
with 3 cups water until remaining 2 1/4 cups. After cold filtered, then drunk after eating, 3 times a day 3/4 cup.
Side Effects Leaf Sambiloto as follows :
Based on the evaluation of Sambiloto's water extract function in-vitro working as insulin secretory in diabetic model mouse, in-vivo study is a further step to test Sambiloto's performance as insulin secretion in the influence of digestion process.
This study aims to determine the effect of Sambiloto's use as a long-term insulin skretagog on the resistance of pancreatic B cells. The immunohistochemical approach to the population and distribution of pancreatic endocrine cells in diabetic model animals given Sambiloto suggests an increase in B cells compared with the normal group.
Increased B-cell populations that occur are followed by increased insulin products secreted in the blood and are able to lower blood sugar levels in the diabetic model to close to normal group values.
Approach of B cell population, insulin level and blood sugar in healthy model / normal in the period of futures known that Sambiloto safe enough to be used in the long term as a precaution of the occurrence of hyperglycemia.
Increased Pancreatic B cell population is a positive indicator in cases of diabetes caused by decreased function / decrease in the number of pancreatic B cells. The approach to the mechanism of increasing the population of B cells is a mystery that needs to get scientific assertion, given the existing Anti Diabetes Drugs (OAD) has not yet led to the improvement of pancreatic B cell population.
Other sources mention, side effects of eating bitter leaf is bitter in the mouth, headache, low blood pressure, bleeding, impaired fertility, risk of miscarriage for pregnant women, autoimmune disease, fatigue and loss of appetite.
Thus about the side effects, chemical content, benefits and benefits of bitter leaves. May be useful….
Source : https://mitalom.com/efek-samping-khasiat-dan-cara-pemakaian-daun-sambiloto-untuk-pengobatan/