Preferring the call with 50k is better for the miner since it frees up 50k in the block for additional transactions hat will actually result in fees.
However, I had a conversation with the person behind a lot of the ethgasstation.info site programming and we found that this is not how actual miners are working. Looking at historical transactions, miners are pretty dumb. They almost always prefer higher gas price and don't look at gas limit, regardless of whether it's high or low.
Miners don't usually account for gas limit until it exceeds 1M or so, in which case they simply ignore it regardless of gas price.
For a demographic that thrives on cost optimization, this was a strange result to find. I'd expect it to change in the future, but who knows.