Less than the setup, for me, the tile activation mechanism of the game annoys me. I prefer tile placement games such as 'Glen More' or 'Lunarchitects', where placing a tile, activates the tiles and the surrounding tiles, but they all activates for themselves, ignoring the surrounding tiles.
I just played Palace if Mad King Ludwig, I liked the way the tiles interacted a lot better. Surburbia has kind of a ton going on.