Yep Carbofuran is (at least as I was reading) really nasty stuff. There really don't seem to be any good pesticides, so I am not sure what large growers are supposed to do to keep food production high enough.
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Yes I think some people were seriously disabled and killed due to exposure. Seem to remember reading about it when researching cholinesterase poising some time back.
Well GM crops would be the alternative but they don't have good press. Natural pest control (using predators like ladybirds can help too) but I'm not sure how effective they are on an industrial scale. Nothing in nature comes for free I suppose!