Leptin, in the hypothalamus, inhibits the feeding center in the brain and as a result appetite is reduced or lost, so that's when we stop eating?
Basically, no matter the amount of leptin in circulation, in Leptin Resistance Syndrome, we continue to eat? Wow!
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Leptin is secreted when plasma insulin level increases. if the receptor functions are not working we continue eating.
Yes, I was educated by your piece.