It's immediately after the end of Spider-Man: Far From Home (2019). Spider-Man (Tom Holland) had been framed by Mysterio who also revealed his true identity, Peter Parker. He and his friends, MJ (Zendaya) and Ned (Jacob Batalon), are hounded by the media, demonized by many, and investigated by the authorities. Frustrated with his situation, he asks Doctor Strange (Benedict Cumberbatch) to do a spell.
This Spider group is a fun group. I love this young group and then there are the veterans. It's a great way to reincorporate the previous Spider-verses and the bonus is getting all these great veteran actors. They are all great at delivering complex characters. There is a bit of redemption for some who ended the previous versions on a down note. This is a good movie by itself as well as a good progression for the MCU.