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The focus of the former president's speech was the current state of the opioid crisis under President Joe Biden's administration, which he criticized for what he described as a regression in progress. He highlighted the alarming statistics surrounding fentanyl—an ultra-potent opioid responsible for countless fatalities—as "ultra-deadly poisons" inflicting severe harm on communities across the nation. According to him, this situation has likely led to the loss of at least 100,000 American lives annually, raising concerns that actual figures could be as high as 300,000 to 400,000.