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Thoughtful responses to the response certainly helps keep the flow going. If I visit a post and see the author continuously repeating "Thank you" "Thanks for the support", I won't leave a comment.

Well, I happened to meet some poeple from various places I've already met, or am going to meet offline, so I chat with them every now and then ;)

And if they're not responding at all, I won't say anything, because I know it'll be ignored.