Before Distributed Exchanges came along, one was forced to do one's "buy-side building" on centralised exchanges. Look at the history of IXCoin and I0Coin for example (two early alt-coins repeatedly "left for dead").
Three or four times over their value climbed to a USD dollar or more, only for the exchange that strong deep buy-side had been built on to use the oh too common in those days "exit strategy" of "oops we got hacked!"
Boom, all the precious BiTCoin we'd build those deep strong buy-sides with vanished and we had to find another (centralised still) exchange to start our work all over again from scratch. (We literally build our buy-sides from one satosh per coin upwards to however high we'd managed to get by the time the exchange "pulled the rug").
Now they are on the HORIZON and Stellar platforms (DEX's: "distributed exchanges") and we are still yet again rebuilding.
Yes we are still also rebuilding on the FreiExchange centralised exchange, but compare prices there versus those on Stellar or HORIZON: it seems clear that the cntralised exchange is mostly used by "dumpers" and thus as a place to get IXCoin and I0Coin and, yes, DeVCoin too, insanely cheap. Let the "dumpers" dump on you there, then bring the coins over to HORIZON or Stellar where your buy-side offers can't be "oh we got hacked" out from under you because your buy-side is the native coin of the platform and stays securely in your own wallet even while being on offer on the buy-side of whatever "assets" you are working with on the platform...
Despite those antics of the centralised exchanges, there was stready profit; by the time they pulled the plug everytyhing we had on them was pure profit, we'd taken out\r initial deposits back and more and more and more...
So definely with good coins, patience waiting out massive downs and building them back up again pays off handsomely!
-MarkM-