Sure.
I'm one of those crazy people that believe the shape of the structure you live in affects your thinking.
I feel not enough exploration has been done in this regard. We just make boxes because they seem efficient. But are they?
The way oranges are stored in a grocery shop is another form of efficiency.
I lived in an eco village south of London once and everyone built their own homes. Only a couple of us ventured outside of the box.
I made a structure that was pentagonal. It was an exciting project.