In the end, however, Johnson was able to flip two remaining holdouts, Reps. Ralph Norman of South Carolina and Keith Self of Texas, who switched to support him, drawing applause from Republicans.
Johnson can now help usher in Trump's ambitious agenda of tax cuts and mass deportations as Republicans sweep to power.
Newly elected House lawmakers started casting votes as Johnson's name was put forward for nomination by the GOP Conference Chair Rep. Lisa McClain, R-Mich.
"No speaker's perfect," she said, adding the goal is to make progress toward shared priorities for the country.
"None of us will get exactly what we want," she said.