He had run the New York race three times before, with his best previous finish coming in 2022, when he was third.
"I know the course," Nageeye said. "Today was two things: survive that race, and my race is after 36 [kilometers; 22 miles]. I was thinking like a cyclist, survive 36K and you're going to win."
Chepkirui was running New York for the first time and pulled away from defending champion Hellen Obiri in the women's race in the last stretch.