It’s certainly important to give these people some time to vent and discuss things. I’ve learned that over the years personally and professionally.
I think what this woman also needs is time outside in the sun and the trees! Both of those have been shown to considerably improve the mental state if she’s not getting enough of it right now. There are certainly places where medication comes into play but as for getting to the root cause of these types of issues, exercise, outdoor time and fresh air quantities are largely never discussed and can be added mostly for free!
At the same time there’s always going to be times where nothing helps and they are just miserable for the rest of their lives. It’s sad but a possibility.