Overusing of drugs for prophylaxis without a doctor's prescription, can lead to drug resistance.
That is a big problem in Africa and South America. I am from Brazil, and during COVID pandemic people overused antibiotics, even those prescribed by MDs. Now, the country faces problems with superresistant bacteria.
I guess there is also another problem, research on neglected diseases. Diseases that happen only in countries where the big pharma countries are not interested in investing. So research for diseases like Malaria, Leishmaniosis, and other parasites is very slow and happens only in labs with small financial support. I hope that you are fine right now and good article!
!1UP
Malaria, typhoid and diseases such as Polio, keeps looking like it cannot be eradicated in this continent, whereas they do not exist in western countries making it look like a propaganda when they are told money is being spent on researching these diseases. Big Pharma are concerned with making money, leaving the non-profit organization to fight the diseases with less funding. While this might be an issue, self-medication is one reason for the mutation of these organisms, making them reoccur and had to cure. Yearly, mosquitoes tend to grow resistance to insecticides that kill them in the previous year, and then the malaria protozoan, plasmodium starts to grow resistance to medication. At one point in time, chloroquine was the go to anti-malaria drug but in 2001, it became less effective for treating Malaria. pubmed