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RE: Life in covid19 testing lab and virology research during the times of pandemic - the crazy year.

in StemSocial3 years ago

Really like how you have written the post. There is one thing I would like to point out though - we should not assume that a vaccine and natural infection may work the same way. There are lots of aspects to it.

Some infection do coffee life time immunity but this is not universal for every infection.

Then it is bit of an over-strech to assume that virus and a subunit vaccine works the same way. Virus comes with it's whole arsenal. So in fact you produce B cells (antibody producing cells) and T cells to whole range of viral proteins and hence the immunity is much broad spectrum than a subunit vaccine. But the arsenal also contains genes that interact with the immune system such as interferon inhibitors or NLRP3 modulators. In a so how the whole game is going to be played out can only be known over time with enough data. A subunit vaccine is a simplistic system. We know most of what it will do inside. Its a controlled system, designed to prepare the immune system.

I mean there is a lot in that post that I would love to discuss. Maybe I will do a post on this topic, it would be interesting. I esp love your question that someone already infected should get a shot or not and would like to cover that bit.

Anyhow, one more thing in your post that nucleocaspid is a protein that binds to nucleic acid (viral RNA in this case). The antibodies you have are against that protein not the viral DNA.

Have a good day 🙂

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Thanks for clearing this all up! I knew I reached out to the right person. No one has been able to explain to me how they would work differently or how the antibodies are to the protein in such a clear way. I agree that not every infection would offer life time immunity. I guess we don't really know until we have done a longitudinal study on it. I look forward to seeing if you do an article on natural immunity and a vaccine afterward.

Thank you once again.