Try vitamin B12 and zinc, that's what I can find if I do a quick search. But the best advice is to consult a homeopath because what I can find is that the restless legs' syndrome is in reality not in your legs but in your brains.
Your complete medical history is needed, because there is not one 'best' treatment. For example, some medication can cause it, other diseases such as rheumatic diseases can increase the risk of getting it or worsen the symptoms.
There are things possible with natural treatment, but not such thing as "oh you gotta do this". Warm foot baths in the evening can help, or cold foot baths in the evening.
It is best to consult a homeopath to get the whole story in line.
I know it's not really in my legs, this problem is in the same area as were Parkinsons disease is situated, namely a shortage of dopamine in the brain. And that makes it very difficult to treat also.