A life that experiences setback is one that is moving forward. No one who is stagnant can be setback, they always live in the back.
One way we know we are moving in the direction of our goals is the veracity of opposition we face.
At some points, we fall to our face, tired, overwhelmed and we feel like quitting. But then, we pick ourselves up and keep moving.
This is why we need solid support base and good friends around us. So when we fall, someone will help us up.