Okay so we need a study which compares the effect of coffee vs the effect of the isolated chlorogenic acid? Cool. If the study were to show coffee is producing a better measurable effect my opinion would have to change but right now we have no such study so your jump to the conclusion that coffee is healthy is a leap of faith.
We already have the studies that show that coffee is beneficial so your "leap of faith" assertion makes no sense. Indeed it is you who are using faith to judge that anything with caffeine in it must be harmful.
Yes the extra information would be useful and we might find out that cholorogenic acid is even better but that bears no relation to this meta-analysis.
Further if we had research comparing decaffeinated coffee with regular coffee we might also find that was healthier but that does not change the findings here.
Just because one component of coffee is more or less healthy does not reverse the original conclusion.
Let's just leave it there because we are not going to agree on this.
Can you link to a study which is proper, randomized controlled with either an animal model or human trials? I don't think the studies you present are clear at all in showing coffee to be healthy.
I would be satisfied if you can show a rat study where there are controls and rats given coffee. Then we see which rats develop diseases and which rats live longer.