one of the most safest drugs
act as analgesic and antipyretic
has weak anti-inflammatory effect
it is metabolized in liver by glutathion so , should not be given to acute or chronic liver patients.
N-acetyl-p-benzoquinone imine (NAPQI) is the substace which is responsible for toxicity.
Toxicity increases with other drugs like anti seizures (carbamazibine,phenytoin)
Trade names: