The Laughing Death - Why Cannibalism is Bad for You
8 years ago in #medicine by thecryptofiend (74)
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Very interesting article! Another reason, why do not eat any meat! Not only the cannibalism is dangerous!
You have a new follower!
We probably don't need to eat meat in modern times but it is likely our ancestors would not have evolved large brains without it. Personally although I still eat meat I can't help but feel uncomfortable with it for animal welfare reasons.
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Disagree. Vegans also get neurodegenerative diseases. And are prone that after a long Vegan diet. It's not healthy it's a religion that puts Animal Life above Human wellbeing and most of the data the quote is from flawed studies and manipulated skewed data. It's very hard for most people to do it right and they start to get malnourish over time which is why most go back to eating meat.
You impress me more and more. Great post!
Thank you so much!
Surprising topic, interesting, creepy :-)
Thanks!
Awesome article! I just read a book about the biological history of cannibalism but the author barely scratched the surface on Kuru and the negative health effects of cannibalism. Definitely interesting to read!
Thank you - what was the book?
Very interesting, thanks!
Does the "normal" prion replicate itself as well or is it generated elsewhere?
Great question! It's a normal protein that is produced in the central nervous system so it doesn't need to replicate.
The abnormal form (PrPsc) replicates because it can change the shape of the regular version (PrPc)- but like I said we don't fully understand the process.
It is possible that there is some bidirectionality in the process in that the abnormal PrPsc can get converted back into the normal PrPc but the current research would suggest that the effect is minimal.
Once introduced the net effect is the accumulation of the abnormal PrPsc. One thing I forgot to say is that the damage may be a secondary result of the abnormal prion protein accumulating.
It may be that the normal PrPc carries out some kind of very vital role in protecting/preserving brain tissue - when it changes to the abnormally shaped version it can no longer do this and so damage accumulates just by normal brain processes.
Synthesis by ribosomes then, like other proteins? I just wondered, because if they reproduced, and what with its helical structure (I looked that up 8-), it almost sounds like a very primitive, pre-DNA form of life, but its being synthesised puts a stop to that idea. Bummer.
So, PrPC is synthesised, and prions multiply by imposing their shape on PrPC, so they don't "procreate" either.
Have they found a reason why prions occur in dead tissue? I mean, what mechanism makes them fold after death to become PrPSc?
Note to self: I should be googling this. Sorry.
Yes exactly.
It is an interesting thing to explore. The problem is they are not really alive by any definition - there is no real metabolic process as such. They are more like viruses in that sense, except even simpler.
Not sure if the process actively happens in dead tissue or not. I suppose it would depend on the physical conditions.
If there are no peri- or postmortem processes changing the shape of PrPC, then there is a patient zero, and this patient zero would have had to be infected in another way, or have a genetic defect that caused the ribosomes to synthesise PrPSc directly, or is the PrPC able to spontaneously transform? Or am I missing an option?
Sorry about the incessant questions, I'm in sponge mode 8-).
The initial patient likely had a mutation to the gene that produces PrPc similar to the sporadic form of CJD - it occurs at a rate of about 1 in every million people if I remember correctly.
Technically such a person would be producing the abnormal protein.
So it is likely that at some point a number of people consumed a relative/friend who had the sporadic mutation and whose body contained the abnormally shaped version.
After doing this, these people then became carriers and subsequently when they died their bodies were consumed and those people became carriers and if their bodies were consumed that spread it onto others...
This way even a very rare disease event i.e. the sporadic mutation can get amplified because of the way that these prion diseases spread.
Further due to the potentially very long incubation period in certain genotypes many cases would be unknown as the people would potentially have died of other causes before they developed Kuru.
No problem I find it fascinating to talk about. It is hard to say with too much certainty about these things as there is still a lot that is not known.
Interesting information. Thank you for sharing!
Thank you for commenting:)
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Truly great report, thank you. I did know about this and it is related to Crushev-jacobs, alzheimers, HIV, and a host of other similar diseases - good job
Thanks. There is a theory that Alzheimers may act in a similar way although no prion has yet been isolated (as far as I know) but one theory is that there is a dysfunction of protein synthesis. HIV can cause a dementia in the terminal stages although this is less common since the development of modern antivirals.
Bonus video for anyone interested in the topic of Cannibalism, Vice put out this little documentary called, The Cannibal Warlords of Liberia, here is the full film
Thank you:)
Wow very good but they say today there are still many ordinary foods that are poisoning us slowly to an earlier death, also its interesting tribes which did not engage in the cannibalism did not suffer from Kuru, a tribe of cannibal women yikes
Yes that is why we need to be wary of what we eat. The effects of many chemicals were not found out until people started suffering illness.
What is the definition of true trust? Two cannibals blowing each other.
Lol!
This was deep! It is in queue for delivery.
Thanks :)
hmmmmm replied to everyone but me.
Don't be so paranoid. I didn't have anything to add to what you said and didn't think you would mind!
There goes my dinner plans!
And my foolproof strategy in The Oregon Trail game.
Lol:)
Wow! I guess I have to cut back ;)
I have had many private chats with you about stuff.
The damage to my body and melon after the car ran me over was extensive and I notice big differences in my abilities, physical and cognitive, there is NO doubt.
Cannibalism being bad for you is the only thing that explains why Ewoks don't eat each other. They are so freaking delicious!!! (Even better than Funyuns)
Lol - they are also quite annoying!
So very interesting this post @cryptofiend, so nice to read too ) So Hillary Clinton,s recent health issues and really strange face pulling videos which are all over youtube , she for one merits a miserable death and good riddance say I
Thanks - I'm not sure Hillary has this - if she did she would most likely already be dead. Also I would not wish this on anyone.
So the moral of the story is - be careful who you eat ;-)
I think if you look deep enough a lot of the taboos and customs particularly around food, stem from this kind of thing. Ancient people knew that bad things came from doing it, they just didn't know how.
At least we have @thecrytofiend to enlighten us ;-)
Yes exactly there is often wisdom in these old taboos. Thank you!
Lol :)
Next Week: Why murder is bad followed by Drowning: Positives and Negatives