This is a pretty though decision, as I think the Internet and the Blockchain are fighting over the first place. However, we do have more or less 82 years left to go - so there might be an even bigger and better invention which, according to our current state of knowledge, we cannot even imagine. Of course there will be some big inventions in the AI sector - considering that every year the computing power almost doubles. With bigger and better computers we are able to have faster and more precise neural networks.
In fact no one can predict what the future will hold for us.