According to some people, there hasn't been much in the way of originality in many aspects of the arts, technology, etc., for a long time. Just different packaging, interpretations or the like.
I think anything we do creatively or to innovate is going to have some roots in things that have happened prior. Science and technology tend to build on what's been done, and writers, artists and musicians all have their influences. Most of us don't operate in a vacuum.
That said, the entertainment industry is a multi-billion dollar a year enterprise, so is the technology sector, and on any given night on television, you can see various iterations of sitcoms, game/contest, medical or police/law or 'reality' programming.
Instead of being concerned with always having something original, in my experience it's been taking the kinds of innovations or creations that you like or are interested in and coming up with your version, and making it good. Creativity and innovation tend to be cyclical. What's out of vogue now comes back at a future date.
So, I know we're always looking for the next cool thing, or breakthrough product or technology, but there are times where that will be incremental, working around the edges, and other times, where giant leaps forward will be made.
If one is truly running out of ideas, then maybe a break from it would be in order. Until the ideas run out, though, there's no use in worrying about when it will happen, because it's bound to happen sooner or late. That doesn't mean innovation or creativity has to stop or that ideas will ever run out. There's always going to be a way to do something better, or different, or interesting, or unique.
Concentrating on what drives you, and what problems people need solved, will help keep creativity and innovation alive.