Chinese scientists have found evidence that a fungus used in traditional Chinese medicine widely sought by the public for its healing powers, also carries anti-cancer benefits.
The scientists found there was an interaction between two anti-cancer compounds in the fungus cordyceps militaris.
The first, cordycepin, was noted in cordyceps militaris in 1950, but how it interacted remained unknown. The second, pentostatin, was first identified from a bacterium and was developed as a commercial drug to treat leukemia and cancers in the 1990s.
“For the first time, we decoded the biosynthesis mechanism of cordycepin in the fungus and during the research we unexpectedly discovered pentostatin,” said Wang Chengshu, head of the research team at the Institute of Plant Physiology and Ecology, a branch of the Shanghai Institutes for Biological Sciences of the Chinese Academy of Sciences.
source:the china daily
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