I would not say that. I am referring to the fact that in most of the continental territory there were no tribe, civilization or people, who, as nomads, did not have a clearly delimited territory. There were many areas that the Europeans conquered without there being an apex of American civilization, that is, without pushing anyone from that place. And that is the main part of the continental territory.
Nor would I say that European culture is fixated on acquisition, perhaps it would be the same for all human culture, if you see the great American civilizations such as the Incas or the Aztecs you could notice how they were also "fixated" on acquisition.