As NASA formally requests proposals for studies on the commercialization of low Earth orbit, another study presented at a congressional hearing May 17 concludes commercial space stations are unlikely to be financially viable in the mid-2020s.
https://www.space.com/40664-commercial-space-stations-pessimistic-outlook.html
The way the ISS is run and costs, I am not surprised no one has figured out how to make a profit, but that doesn't mean another space station wouldn't be profitable.