Painting or drawing on a computer is not difficult as long as we have the right peripherals (display tablet, for example). The technique differs in that we have much more freedom to modify the image on the computer (undo / redo, mix 2d and 3d techniques and many more, actually the number of combinations is unlimited;)). Thus, the main difference (except that the image is digital) is that the image can always be modified by any techniques. Although natural media can also be mixed with one another, it can be mixed up so that you will not be able to do anything about it (it will be overflowing and therefore destroyed). In my opinion, this is the difference between natural media and digital media.