I think the answers we all seek would need to include all aspects of our experience. We build on our understanding, starting with trying to define rules and connections from our observations.
We observe the world around us -
Physics, Chemistry, Biology
We also observe ourselves -
philosophy, psychology, sociology, spirituality...
We are not lost, we have left ourselves breadcrumb trails. We have the power of the internet so that we can connect together, giving voice to our perspectives, so that we can find our way :)