I'm surprised supercooling a liver would work - seems like crystals would form somewhere in a liver - I wonder how they prevent that from happening?
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I'm surprised supercooling a liver would work - seems like crystals would form somewhere in a liver - I wonder how they prevent that from happening?
They used a specialised solution to protect the liver sinusoids and epithelial cells from the potential damage of freezing and ice crystals. Polyethylene glycol (PEG) was used to protect the epithelial cells and a glucose derivative 3-O-methyl-D-glucose (3-OMG) was used to protect from supercooling.
More information can be found from the study here:
http://www.nature.com/nm/journal/v20/n7/full/nm.3588.html