Laser powered solar sails could be used to achieve that kind of speed. They have already been proven to be useable (IKAROS-project) but the addition of driving it with a laser rather than with solar wind is still a huge step. Still, the relatily short distance removes many of the problems (like the insane lensen which would be required to be able to focus the laser beam hundreds of lightyears away.)
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To quote Dr. Sagan: “The sky calls to us. If we do not destroy ourselves, we will one day venture to the stars.”