Great post, I'm with you 100% on the tried once list. It's the only way to live!
However, if you want to get REAL crazy and try the ACTUAL most dangerous drug in the world... Get yourself some "Flakka" or "The Crocodile Drug"...
I will say though, I don't recommend it... It rots your flesh away. Just one time will leave you scarred and can potentially leave you brain damaged.