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No real issues, just like others , like Emsisoft.

EAM is some good stuff, but they serve slightly different purposes. Malwarebytes is more of a complimentary software to an existing AV, and does more in terms of preventative measures. EAM is faster and has a higher detection rate, but it's my understanding that this is because it's based on signature analysis, so it only does anything after you've been infected.