There's a lot of sleep deprivation experiments made on animals, with the resultat of animals dying after 6-8 days of sleep deprivation due to damage of alimentary track . The brain wasn't damaged at all.
In fact it's very well known that the brain is in fact even more active when sleeping.
So, the main theory about sleep nowadays is, during the day the brain is "computing" signals from outside world, at night it switches to computing signals from inner organs, which signals were "neglected" during the day.
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