The former secretary general of FIFA has had his 10-year ban from football upheld by the Court of Arbitration for Sport on Friday.
Jerome Valcke served in the position for eight years during Sepp Blatter's presidency but was sacked in 2016 and handed a decade-long ban from all football-related activity by the FIFA ethics committee.
His appeal was heard in October, and on Friday it was dismissed by CAS.
"The offences found to have been committed by Jerome Valcke were cumulatively of a serious degree of gravity," CAS said in its statement, adding the ban and fine of 100,000 Swiss francs (£76,600) "were wholly proportionate."
Valcke, a former TV presenter from France, was a FIFA marketing executive and before being fired in 2006.
He became then-president Blatter's right-hand man the next year.
Valcke was dismissed a second time in January 2016 after being implicated in irregular World Cup ticket and broadcast rights sales, plus expense abuses including personal use of private jets.
The FIFA ethics committee banned Valcke for 12 years, with an additional charge of destroying evidence.
FIFA's appeal panel cut the ban by two years because it judged the broadcasting deal charge was not proven.
Valcke denied all wrongdoing.