Very, VERY rarely (less than one in a billion, according to the Bhagavad Gita), a fully self-realized person appears on this planet, who never suffers such setbacks. Nearly all of us MUST experience some "dark night of the soul" to make any kind of spiritual progress, but particularly in cultures touched by "the West" (nearly everywhere in the world now) the fact that such experience is not pleasurable leads to a motivation to avoid such depression, inner conflict, and suffering.
ALL of it could be turned to our benefit, but we aren't taught and given the tools of meditation and self-examination very early in life to enable this; that is very uncomfortable for most parents to consider. and diametrically opposed to the central cultural ethos and practices of nearly all societies, so they are considered fodder for senior academic pursuits in philosophy, ethics, morality, etc.
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