Hello everyone..
Today I would love to share another research in steemit. This study was to search correlation between the severity of depression and serum interleukin-6 (IL-6) level in patients with uncontrolled ashtma bronchial. It was conducted at Mohammad Husen Hospital of Palembang , Indonesia.
Background
Psychiatric signs and symptoms are common in patients with chronic somatic diseases such as bronchial asthma. From a neurobiology perspective, several hypotheses explain the onset of psychiatric symptoms in patients with asthma. Systemic inflammation becomes the key link between these conditions and studies show that cytokines have an indirect role in the neurotransmission of the central nervous system. Interleukin-6 (IL-6) serum is found in various inflammatory diseases. Interestingly, elevated serum IL-6 levels were found in asthmatic patients.
Methods
The study design was a correlative analytic design with a cross sectional approach. The study was conducted at Polynomial Allergy Immunology of Mohammad Husen Hospital. This study start from July 2014 to December 2014. Subjects of the study were 42 patients with uncontrolled asthma and depression based on the BDI score (Beck Depression Inventory). Serum IL-6 levels were examined.
Results
Serum IL-6 concentration was obtained with median 1.78 (0.56-6.04) pg/mL. The severity of depression based on the BDI score obtained mild depression 29 subjects (69%), severe depression 7 subjects (16.7%) and moderate depression 6 subjects (14.3%). There was a weak positive correlation (p = 0.018, r = 0.364) between severity of depression and serum interleukin 6 levels in uncontrolled bronchial asthma.
Conclusion
The higher levels of Interleukin-6, the more severe depression in uncontrolled bronchial asthma patients.
Reference
- Global strategy for asthma management and prevention 2012. Available at www.ginasthma.org
- Bratek A, Zawada K, Julia B, Beil S, Sozanska E, Krysta K et al. Depressiveness, symptoms of anxiety and cognitive dysfunctions in patients with asthma and chronic obstructive pulmonary disease (COPD) : possible associations with inflammation markers : a pilot study. J Neural Transm 2014.
- O’Donovan A, Hughes BM, Slavich GM, Lynch L, Cronin MT, O’Farrelly C, Malone KM (2010) Clinical anxiety, cortisol and interleukin-6: evidence for specificity in emotion-biology relationships. Brain Behav Immun 2010; 24:1074–1077.
What is depression that makes some of them asthmatic?
Asma dapat menyebabkan depresi...
bahaya juga pak dok serangan Asthmatic ini..
Kalo jangka panjang, memang asma sangat mengganggu dan melelahkan bagi pasien..
Asli bakal jadi satu buku Kedokteran Blockchain
Heheheh.. kayaknya cocok bang 😁
Terimakasih edukasinya @razack-pulo
Semoga kita selalu diberi kesehatan oleh yg maha kuasa
Amiiin ya tambal alamin... trims ya :)
Oh ureng saket sesak nyan pak,Pu na menular penyakit nyan pak ?
Menyo asma Hana menular. Tetapi diturunkan ke anaknya. Sebab asma termasuk salah satu penyakit alergi
Izin dok...apakah asma bronchial ini bisa di
Sembuh kan secara total..?
Sembuh secara total tanpa penggunaan obat, sepertinya sulit. Sebab asma ini kambuh kambuhan, tergantun pada faktor pencetus, misalnya debu, cuaca dingin, stres, makanan, dll..
Wah banyak info yang bermanfaat disini, saya juga mengalami asma, apakah asma yang saya alami termasuk asma bronkial? Ada perbedaan gak @razack-pulo?
Setiap asma, memang asma bronkusku, sebab ia membuat sempit saluran bronchus, salah satu saluran napas yg besar
akhirnya ada juga tulisan tentang kesehatan dari dokter @razack-pulo. Meski saya lebih suka menyisir tulisan travel dan culinary nya hehhehehe.... Kapan ada di Bireuen pak?
Hehe. Traveling tetap saya tulis,
Selalu menarik mengikuti tulisan dokter . . :)
Siip. Thank ya @tanyo :)