well, if you go back far enough, further than galileo even, the alchemists of old did nothing but empirical research, would have been quacks now but in essence went over whole combinations to gather datasets, including some of my personal heroes like Theo Paracelsus they were very very early pioneers ... in chemistry ... in biology, in lots of things :)
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Theo Paracelsus. I have to look that up.
Measuring and collecting data...it doesn't seem glamorous, but is the heart of good research.
Thanks for your comment.