Great post! RNA does have a lot of variability and a ton of different potential applications. However, its greatest weakness is poor stability. Most RNA doesn't last long at room temperature. This isn't a weakness for normal cellular function (in fact its short half -life is essential ), but low stability does hinder research efforts and the ability to create tools/medicines from it.
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Yeah its poor stability is pretty much why DNA is better for storing and passing information from generation to generation as it is quite vital for information to remain unaltered. The RNAs in the prebiotic world were suggested to have methylated backbones and this somehow made them much more stable than they would normally be (i dare to say, almost as stable as DNA :p). It sucks that its poor stability has made its diverse use in therapy a bit far from reality.
Thanks for reading through ! Cheers !