It's like if you had lost the key to your 400k house.
Everyone has it own scale for painful life experiences. However, I realized recently that instead of dwelling on past mistakes and instead of spending tremendous brain power trying to get the most out of a "lost cause", we can look out for new opportunities that will bring us more that what we lost. Be it monetary, or in form of wisdom or relationships. And we often forget that our greatest wealth is our health.