Wow! I asked for a little, I got a big fill!
All drugs have half life and duration in which they are active. Some can even last for more than a day before excreted. Some even undergo enetero circulation in the body I. E they are reabsorbed in the large intestine and passes through the body system again still active e.g oral contraceptives.Re-absorption into entero circulation...got it!
In a nutshell, there is no specific general time frame for all drugs, they all have individuals duration at which they can stay in the body. Once they get to the liver, they are biotransformed by Cytochrome P450 enzyme and excreted either through urine or faeces. Drugs will most likely accumulate in the body if the liver is not functional or maybe when the enzyme that is meant to catabolize the drug has been inhibited competitively by another drug.Understood! our Liver is one essential organ we shouldn't joke with.
Taking mebendazole aka actifed with alcohol is like getting closer to hell. It produces a disulfiram like effect. An unpleasant reaction that will make a chronic alcohol consumer to desist. Likewise taking paracetamol with alcohol.Thanks for this waning. I would never try it.
This is a complete answer to my question... I had a good time here.
Thanks brother @cyprianj
This is the importance of interacting with post. The noble gentle bot just favoured you bro.
Congratulations
Haha... Really???
Thanks @gentlebot Hmm, you are right @cyprianj thanks for getting my attention. You started it, your article was superb and educative.
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