In my personal opinion I believe that transhumanism can be of great help in some people that, as in the case that you commented, lack a limb of your body necessary to perform daily activities or in people who have organs that do not work properly and that may be replaced by artificial organs that guarantee their proper functioning in order to improve health. Now, I do not agree to use transhumanism to be super athletes with super powers or to extend our life time on earth because I believe it is not from God.
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