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Sorry i missed this, nope don't think i'm gonna try tranquilizers. But i heard there's some spiritual moments to be had!

Thanks for your reply. To take these substances is usually the job of a shaman. Like a whole village would have one shaman who is altering his consciousness to help others.
In the modern days this has changed a bit. Still, it is not for everybody. Both, shaman and non-shaman, are playing an important role for societies. The bummer is that shamans get hunted by the government since a long time. Put to jail or get killed for exploring consciousness first hand. Peace.