If you're not used to it, yeah. There are some strains that provide an uplifting, energetic and happy mood. When it was illegal, it was always a surprise. Now we have fancy packaging with lab results and online reviews to look over before purchasing.
A once per year heavy dose of psilocybin works great for depression. At least, it does for me anyway.
I'm such a good influence!
Those pills are probably a way better idea. I'm not sure if I want to experiment with them though. There's one side effect that scares the crap out of me, but it's rare.