Well, I'd say you're getting to a part of the topic that might become a slippery slope, simply because there enough material for a dissertation there.
Not only can we say that life isn't necessarily "fair" from a genetic perspective (because we are NOT all "born equal"), but then we also have to factor in our individual perceptions of "fairness" and what things like success mean. For example, I have no interest in some Dude Bob's teleseminar on how to flip real estate so I can buy a mansion and a Lamborghini. His definition of "successful" is meaningless to me. Makes it difficult to define the playing field, let alone the game, itself.