It is possible that it is psychosomatic, but unlikely in this case. They think it could be that the nerve signals aren't being interpreted well in the brain. I think it is something different again though, but not sure what the cause or treatment would be.
I think it is less anguish and more disappointment in the way it has all played out. Perhaps if was religious, I would have someone to blame or rely on, perhaps saying that it is retribution for a past life or something :)
The risk of spiralling is quite high though for these kinds of things. Mild stroke patients are something like 10-20x more likely to suicide than normal population and I think it comes down to the frustration and lack of clear steps for anything that can help.