A feeling that nothing matters and I might as well just escape
I've actually pondered this before, and to overly simplify the concept, I came to this conclusion: if nothing really matters, then it's simply not worth worrying about. May as well be happy about whatever it is we have! (Easier said than done, yes)
In either case, it sounds like a change of routine would help you place things in perspective, so that you can get a better sense of what matters specifically to you. After all, this your life and experiences.
Please let us know what ends up working for you!